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Hypothermia differentially modulates the formation and decay of NBS1, γH2AX and 53BP1 foci in U2OS cells exposed to gamma radiation

In studies on the mechanism of DNA damage response where ionizing radiation is used as the DNA damaging agent, cells are often exposed to ionizing radiation on melting ice (corresponding to 0.8 °C). The purpose of this procedure is to inhibit cellular processes i.e. DNA repair. Low temperature at ex...

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Detalles Bibliográficos
Autores principales: Płódowska, Magdalena, Krakowiak, Wiktoria, Węgierek-Ciuk, Aneta, Lankoff, Anna, Szary, Karol, Lis, Krzysztof, Wojcik, Andrzej, Lisowska, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989987/
https://www.ncbi.nlm.nih.gov/pubmed/35393518
http://dx.doi.org/10.1038/s41598-022-09829-y