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SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression

Glioblastoma (GBM) is a fatal malignancy caused by dysregulation of cellular signal transduction. Internalization plays a key role in maintaining signalling balance. Previous reports showed that Sortilin related VPS10 domain containing receptor 3 (SorCS3) has the ability to regulate internalization....

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Detalles Bibliográficos
Autores principales: Zhang, Yanqiu, Li, Yue, Fan, Yuhua, Zhang, Xiaoyuan, Tang, Zhihong, Qi, Jing, Zhao, Baoshan, Li, Fuyuan, Chen, Xiaofeng, Liang, Huan, Xu, Haiyan, Li, Dongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8989992/
https://www.ncbi.nlm.nih.gov/pubmed/35393432
http://dx.doi.org/10.1038/s41419-022-04753-5