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Incidence and impact of brain metastasis in patients with hereditary BRCA1 or BRCA2 mutated invasive breast cancer

Patients with hereditary mutations in BRCA1 or BRCA2 (gBRCA1/2) and breast cancer have distinct tumor biology, and encompass a predilection for brain metastasis (BM). We looked into baseline risk of BMs among gBRCA1/2 patients. Patients with gBRCA1/2, stage I-III invasive breast cancer seen between...

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Detalles Bibliográficos
Autores principales: Garber, Haven R., Raghavendra, Akshara Singareeka, Lehner, Michael, Qiao, Wei, Gutierrez-Barrera, Angelica M., Tripathy, Debu, Arun, Banu, Ibrahim, Nuhad K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990006/
https://www.ncbi.nlm.nih.gov/pubmed/35393462
http://dx.doi.org/10.1038/s41523-022-00407-z