CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity

Natural killer (NK) cells are known to mediate killing of various cancer types, but tumor cells can develop resistance mechanisms to escape NK cell-mediated killing. Here, we use a “two cell type” whole genome CRISPR-Cas9 screening system to discover key regulators of tumor sensitivity and resistanc...

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Detalles Bibliográficos
Autores principales: Bernareggi, Davide, Xie, Qi, Prager, Briana C., Yun, Jiyoung, Cruz, Luisjesus S., Pham, Timothy V., Kim, William, Lee, Xiqing, Coffey, Michael, Zalfa, Cristina, Azmoon, Pardis, Zhu, Huang, Tamayo, Pablo, Rich, Jeremy N., Kaufman, Dan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990014/
https://www.ncbi.nlm.nih.gov/pubmed/35393416
http://dx.doi.org/10.1038/s41467-022-29469-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990014/
https://www.ncbi.nlm.nih.gov/pubmed/35393416
http://dx.doi.org/10.1038/s41467-022-29469-0

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