Targeting adipocytic discoidin domain receptor 2 impedes fat gain while increasing bone mass

Obesity is closely associated with low-bone-mass disorder. Discoidin domain receptor 2 (DDR2) plays essential roles in skeletal metabolism, and is probably involved in fat metabolism. To test the potential role of DDR2 in fat and fat-bone crosstalk, Ddr2 conditional knockout mice (Ddr2(Adipo)) were...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyu, Li, Jing, Zhao, Liting, Chen, Yazhuo, Cui, Zhijun, Xu, Taotao, Li, Xu, Wu, Shufang, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990016/
https://www.ncbi.nlm.nih.gov/pubmed/34645939
http://dx.doi.org/10.1038/s41418-021-00887-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990016/
https://www.ncbi.nlm.nih.gov/pubmed/34645939
http://dx.doi.org/10.1038/s41418-021-00887-9

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