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Successive remodeling of IgG glycans using a solid-phase enzymatic platform

The success of glycoprotein-based drugs in various disease treatments has become widespread. Frequently, therapeutic glycoproteins exhibit a heterogeneous array of glycans that are intended to mimic human glycopatterns. While immunogenic responses to biologic drugs are uncommon, enabling exquisite c...

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Detalles Bibliográficos
Autores principales: Hsu, Yen-Pang, Verma, Deeptak, Sun, Shuwen, McGregor, Caroline, Mangion, Ian, Mann, Benjamin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990068/
https://www.ncbi.nlm.nih.gov/pubmed/35393560
http://dx.doi.org/10.1038/s42003-022-03257-4