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Successive remodeling of IgG glycans using a solid-phase enzymatic platform
The success of glycoprotein-based drugs in various disease treatments has become widespread. Frequently, therapeutic glycoproteins exhibit a heterogeneous array of glycans that are intended to mimic human glycopatterns. While immunogenic responses to biologic drugs are uncommon, enabling exquisite c...
Autores principales: | Hsu, Yen-Pang, Verma, Deeptak, Sun, Shuwen, McGregor, Caroline, Mangion, Ian, Mann, Benjamin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990068/ https://www.ncbi.nlm.nih.gov/pubmed/35393560 http://dx.doi.org/10.1038/s42003-022-03257-4 |
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