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Collateral sensitivity to pleuromutilins in vancomycin-resistant Enterococcus faecium

The acquisition of resistance to one antibiotic sometimes leads to collateral sensitivity to a second antibiotic. Here, we show that vancomycin resistance in Enterococcus faecium is associated with a remarkable increase in susceptibility to pleuromutilin antibiotics (such as lefamulin), which target...

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Detalles Bibliográficos
Autores principales: Li, Qian, Chen, Shang, Zhu, Kui, Huang, Xiaoluo, Huang, Yucheng, Shen, Zhangqi, Ding, Shuangyang, Gu, Danxia, Yang, Qiwen, Sun, Hongli, Hu, Fupin, Wang, Hui, Cai, Jiachang, Ma, Bing, Zhang, Rong, Shen, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990069/
https://www.ncbi.nlm.nih.gov/pubmed/35393429
http://dx.doi.org/10.1038/s41467-022-29493-0