Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4

Nicotinamide phosphoribosyltransferase (NAMPT), alongside being a crucial enzyme in NAD synthesis, has been shown to be a secreted protein (eNAMPT), whose levels are increased in patients affected by immune-mediated disorders. Accordingly, preclinical studies have highlighted that eNAMPT participate...

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Detalles Bibliográficos
Autores principales: Colombo, Giorgia, Travelli, Cristina, Porta, Chiara, Genazzani, Armando A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990213/
https://www.ncbi.nlm.nih.gov/pubmed/35402885
http://dx.doi.org/10.1016/j.isci.2022.104147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990213/
https://www.ncbi.nlm.nih.gov/pubmed/35402885
http://dx.doi.org/10.1016/j.isci.2022.104147

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