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Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4

Nicotinamide phosphoribosyltransferase (NAMPT), alongside being a crucial enzyme in NAD synthesis, has been shown to be a secreted protein (eNAMPT), whose levels are increased in patients affected by immune-mediated disorders. Accordingly, preclinical studies have highlighted that eNAMPT participate...

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Detalles Bibliográficos
Autores principales:	Colombo, Giorgia, Travelli, Cristina, Porta, Chiara, Genazzani, Armando A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990213/ https://www.ncbi.nlm.nih.gov/pubmed/35402885 http://dx.doi.org/10.1016/j.isci.2022.104147

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