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PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt–Jakob Disease
Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder caused by the conformational conversion of the prion protein (PrP(C)) into an abnormally folded form, named prion (or PrP(Sc)). The combination of the polymorphism at codon 129 of the PrP gene (coding either methionine or...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990253/ https://www.ncbi.nlm.nih.gov/pubmed/35401151 http://dx.doi.org/10.3389/fnagi.2022.848991 |