PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt–Jakob Disease

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder caused by the conformational conversion of the prion protein (PrP(C)) into an abnormally folded form, named prion (or PrP(Sc)). The combination of the polymorphism at codon 129 of the PrP gene (coding either methionine or...

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Detalles Bibliográficos
Autores principales: Cazzaniga, Federico Angelo, Bistaffa, Edoardo, De Luca, Chiara Maria Giulia, Portaleone, Sara Maria, Catania, Marcella, Redaelli, Veronica, Tramacere, Irene, Bufano, Giuseppe, Rossi, Martina, Caroppo, Paola, Giovagnoli, Anna Rita, Tiraboschi, Pietro, Di Fede, Giuseppe, Eleopra, Roberto, Devigili, Grazia, Elia, Antonio Emanuele, Cilia, Roberto, Fiorini, Michele, Bongianni, Matilde, Salzano, Giulia, Celauro, Luigi, Quarta, Federico Giuseppe, Mammana, Angela, Legname, Giuseppe, Tagliavini, Fabrizio, Parchi, Piero, Zanusso, Gianluigi, Giaccone, Giorgio, Moda, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990253/
https://www.ncbi.nlm.nih.gov/pubmed/35401151
http://dx.doi.org/10.3389/fnagi.2022.848991

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