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Monoclonal Antibodies as Probes to Study Ligand-Induced Conformations of Troponin Subunits

Striated muscle contraction and relaxation is regulated by Ca(2+) at the myofilament level via conformational modulations of the troponin complex. To understand the structure–function relationship of troponin in normal muscle and in myopathies, it is necessary to study the functional effects of trop...

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Detalles Bibliográficos
Autores principales: Rasmussen, Monica, Jin, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990283/
https://www.ncbi.nlm.nih.gov/pubmed/35399275
http://dx.doi.org/10.3389/fphys.2022.828144