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Inhibition of adult T‐cell leukemia cell proliferation by polymerized proanthocyanidin from blueberry leaves through JAK proteolysis

We have previously reported that the proanthocyanidin (PAC) fraction of blueberry leaf extract (BB‐PAC) inhibits the proliferation of HTLV‐1‐infected adult T‐cell leukemia (ATL) by inducing apoptosis. In the present study, we further analyzed the structure of BB‐PAC and elucidated the molecular mech...

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Detalles Bibliográficos
Autores principales: Ichikawa, Tomonaga, Sugamoto, Kazuhiro, Matsuura, Yasushi, Kunitake, Hisato, Shimoda, Kazuya, Morishita, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990289/
https://www.ncbi.nlm.nih.gov/pubmed/35100463
http://dx.doi.org/10.1111/cas.15277