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Anti-Fungal Drug Anidulafungin Inhibits SARS-CoV-2 Spike-Induced Syncytia Formation by Targeting ACE2-Spike Protein Interaction

Drug repositioning continues to be the most effective, practicable possibility to treat COVID-19 patients. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus enters target cells by binding to the ACE2 receptor via its spike (S) glycoprotein. We used molecular docking-based virtua...

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Detalles Bibliográficos
Autores principales: Ahamad, Shahzaib, Ali, Hashim, Secco, Ilaria, Giacca, Mauro, Gupta, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990323/
https://www.ncbi.nlm.nih.gov/pubmed/35401674
http://dx.doi.org/10.3389/fgene.2022.866474