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Mir-454-3p induced WTX deficiency promotes hepatocellular carcinoma progressions through regulating TGF-β signaling pathway

Background: Wilms tumor gene on X chromosome (WTX) is an X-linked tumor suppressor gene in Wilms tumor; however, however, the molecular mechanism of WTX in the occurrence and development of HCC has not been reported. Methods: The expression of miR-454-3p and WTX wre analyzed in 32 matched human HCC...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Zheng, Juan, Yang, Shengqian, Zong, Qibei, Wang, Zhiwen, Liao, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990407/
https://www.ncbi.nlm.nih.gov/pubmed/35399726
http://dx.doi.org/10.7150/jca.67478