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ACOT12-mediated acetyl-CoA hydrolysis suppresses intrahepatic cholangiocarcinoma metastasis by inhibiting epithelial-mesenchymal transition

Intrahepatic cholangiocarcinoma (ICC) is the most common malignant bile duct tumor in the liver and the second most common primary liver cancer with increasing morbidity and poor prognosis. Metabolic aberration plays key roles in cancer progression. As a key metabolic intermediate, acetyl-CoA accumu...

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Detalles Bibliográficos
Autores principales: Zhou, Xu, Zhou, Yu, Shao, Weiqing, Hong, Liang, Lu, Ming, Zhu, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990409/
https://www.ncbi.nlm.nih.gov/pubmed/35399720
http://dx.doi.org/10.7150/jca.62169