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GPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways

G-protein-coupled receptors (GPCRs) signaling is critical to cell differentiation and activation. However, the function of GPCRs in osteoclast differentiation and activation remains unclear. We found that the G-protein coupled receptor 125 (GPCR 125) gene (Gpr125) gene was highly expressed in osteoc...

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Detalles Bibliográficos
Autores principales: Tang, Chen-Yi, Wang, He, Zhang, Yan, Wang, Zhongliang, Zhu, Guochun, McVicar, Abigail, Li, Yi-Ping, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990458/
https://www.ncbi.nlm.nih.gov/pubmed/35414778
http://dx.doi.org/10.7150/ijbs.70620