Cargando…

GPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways

G-protein-coupled receptors (GPCRs) signaling is critical to cell differentiation and activation. However, the function of GPCRs in osteoclast differentiation and activation remains unclear. We found that the G-protein coupled receptor 125 (GPCR 125) gene (Gpr125) gene was highly expressed in osteoc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Chen-Yi, Wang, He, Zhang, Yan, Wang, Zhongliang, Zhu, Guochun, McVicar, Abigail, Li, Yi-Ping, Chen, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990458/ https://www.ncbi.nlm.nih.gov/pubmed/35414778 http://dx.doi.org/10.7150/ijbs.70620

Ejemplares similares

F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NFκB signaling pathways
por: Zhang, Yan, et al.
Publicado: (2020)

Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C‐Src and inhibiting NF‐κB, MAPK and AKT pathways
por: Zhi, Xin, et al.
Publicado: (2020)

Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB
por: Quan, Gui-Hua, et al.
Publicado: (2015)

Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling‐mediated TRAF6 and c‐Src recruitment and NF‐κB, MAPK and Akt pathways
por: Chen, Huiwen, et al.
Publicado: (2020)

Deacylcynaropicrin Inhibits RANKL-Induced Osteoclastogenesis by Inhibiting NF-κB and MAPK and Promoting M2 Polarization of Macrophages
por: Li, Zhikun, et al.
Publicado: (2019)

Nepetin inhibits osteoclastogenesis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signalling pathway, and autophagy
por: Chu, Binxiang, et al.
Publicado: (2020)

Protective Effects of Punicalagin on Osteoporosis by Inhibiting Osteoclastogenesis and Inflammation via the NF-κB and MAPK Pathways
por: Wang, Wei, et al.
Publicado: (2020)

Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways
por: Hu, Xuantao, et al.
Publicado: (2020)

Myostatin Promotes Osteoclastogenesis by Regulating Ccdc50 Gene Expression and RANKL-Induced NF-κB and MAPK Pathways
por: Zhi, Xin, et al.
Publicado: (2020)

Galangin suppresses RANKL‐induced osteoclastogenesis via inhibiting MAPK and NF‐κB signalling pathways
por: Li, Xiucheng, et al.
Publicado: (2021)

NF-κB-Mediated Regulation of Osteoclastogenesis
por: Boyce, Brendan F., et al.
Publicado: (2015)

Aspirin inhibits osteoclastogenesis by suppressing the activation of NF-κB and MAPKs in RANKL-induced RAW264.7 cells
por: Zeng, Yan-Ping, et al.
Publicado: (2016)

Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation
por: Guo, Wen, et al.
Publicado: (2021)

KMUP-1 Suppresses RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss: Roles of MAPKs, Akt, NF-κB and Calcium/Calcineurin/NFATc1 Pathways
por: Liou, Shu-Fen, et al.
Publicado: (2013)

Stachydrine prevents LPS‐induced bone loss by inhibiting osteoclastogenesis via NF‐κB and Akt signalling
por: Meng, Jiahong, et al.
Publicado: (2019)

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway
por: Wu, Mengrui, et al.
Publicado: (2017)

l‐tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK‐TRAF6 interactions and inhibiting NF‐κB and MAPK pathways
por: Zhi, Xin, et al.
Publicado: (2019)

Sesamolin Protects Mice From Ovariectomized Bone Loss by Inhibiting Osteoclastogenesis and RANKL-Mediated NF-κB and MAPK Signaling Pathways
por: Yang, Xue, et al.
Publicado: (2021)

Author Correction: Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway
por: Wu, Mengrui, et al.
Publicado: (2019)

Palmitoleic Acid Inhibits RANKL-Induced Osteoclastogenesis and Bone Resorption by Suppressing NF-κB and MAPK Signalling Pathways
por: van Heerden, Bernadette, et al.
Publicado: (2017)

α-Mangostin inhibits LPS-induced bone resorption by restricting osteoclastogenesis via NF-κB and MAPK signaling
por: Zhang, Wenkan, et al.
Publicado: (2022)

Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways
por: Tang, Chen-Yi, et al.
Publicado: (2021)

Knockout and Double Knockout of Cathepsin K and Mmp9 reveals a novel function of Cathepsin K as a regulator of osteoclast gene expression and bone homeostasis
por: Zhu, Guochun, et al.
Publicado: (2022)

Correction: Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways
por: Tang, Chen-Yi, et al.
Publicado: (2022)

Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis
por: Lee, Won-Seok, et al.
Publicado: (2018)

Casticin suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating the AKT/ERK and NF-κB signaling pathways
por: Yang, Fan, et al.
Publicado: (2023)

Staphylococcus Aureus Induces Osteoclastogenesis via the NF-κB Signaling Pathway
por: Ren, Li-Rong, et al.
Publicado: (2017)

Magnoflorine Suppresses MAPK and NF-κB Signaling to Prevent Inflammatory Osteolysis Induced by Titanium Particles In Vivo and Osteoclastogenesis via RANKL In Vitro
por: Sun, Zhenyu, et al.
Publicado: (2020)

20(S)-Protopanaxadiol Inhibits Titanium Particle-Induced Inflammatory Osteolysis and RANKL-Mediated Osteoclastogenesis via MAPK and NF-κB Signaling Pathways
por: Pan, Chenhao, et al.
Publicado: (2019)

A novel BRD4 inhibitor suppresses osteoclastogenesis and ovariectomized osteoporosis by blocking RANKL-mediated MAPK and NF-κB pathways
por: Liu, Ying, et al.
Publicado: (2021)

Lithium chloride inhibits titanium particle-induced osteoclastogenesis by inhibiting the NF-κB pathway
por: Hu, Xuanyang, et al.
Publicado: (2017)

SHIP1 Activator AQX-1125 Regulates Osteogenesis and Osteoclastogenesis Through PI3K/Akt and NF-κb Signaling
por: Xie, Xudong, et al.
Publicado: (2022)

Peptide targeting of lysophosphatidylinositol-sensing GPR55 for osteoclastogenesis tuning
por: Mosca, Maria Giovanna, et al.
Publicado: (2021)

Staphylococcus aureus Protein A induces osteoclastogenesis via the NF-κB signaling pathway
por: Ren, Li-Rong, et al.
Publicado: (2017)

Schistosoma japonicum cystatin suppresses osteoclastogenesis via manipulating the NF-κB signaling pathway
por: Chen, Yu, et al.
Publicado: (2021)

Strontium Ranelate Inhibits Osteoclastogenesis through NF-κB-Pathway-Dependent Autophagy
por: Wu, Dongle, et al.
Publicado: (2023)

Oridonin Attenuates Thioacetamide-Induced Osteoclastogenesis Through MAPK/NF-κB Pathway and Thioacetamide-Inhibited Osteoblastogenesis Through BMP-2/RUNX2 Pathway
por: Jin, XiaoLi, et al.
Publicado: (2023)

Diallyl disulfide alleviates inflammatory osteolysis by suppressing osteoclastogenesis via NF-κB–NFATc1 signal pathway
por: Yang, Jing, et al.
Publicado: (2019)

Cimifugin Suppresses NF-κB Signaling to Prevent Osteoclastogenesis and Periprosthetic Osteolysis
por: Duan, Juan, et al.
Publicado: (2021)

TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling
por: Yang, Wanlei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_anraehooovlg9olcbd831k5ucl