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The suppressive functions of Rora in B lineage cell proliferation and BCR/ABL1-induced B-ALL pathogenesis
RORA plays an important role in regulating circadian rhythms, inflammation, metabolism and cellular development. Herein, we explore the roles of Rora in B cell proliferation and differentiation, as well as in Ph(+) B-ALL. By using Rora(loxp/loxp) Mx-1-Cre mice, Rora was deleted in hematopoietic cell...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990459/ https://www.ncbi.nlm.nih.gov/pubmed/35414788 http://dx.doi.org/10.7150/ijbs.68939 |