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The suppressive functions of Rora in B lineage cell proliferation and BCR/ABL1-induced B-ALL pathogenesis

RORA plays an important role in regulating circadian rhythms, inflammation, metabolism and cellular development. Herein, we explore the roles of Rora in B cell proliferation and differentiation, as well as in Ph(+) B-ALL. By using Rora(loxp/loxp) Mx-1-Cre mice, Rora was deleted in hematopoietic cell...

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Detalles Bibliográficos
Autores principales: Li, Ning, Wang, Nan, He, Wei, Feng, Yunyu, Qiu, Qiang, Qiu, Huandi, Zheng, Li, Yin, Yuexia, Wang, Bochuan, Sun, Yuanyuan, Pan, Cong, Sample, Klarke M., Huang, Juan, Su, Zhiguang, Li, Zhihui, Zhang, Haojian, Hu, Yiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990459/
https://www.ncbi.nlm.nih.gov/pubmed/35414788
http://dx.doi.org/10.7150/ijbs.68939