Enhanced pentose phosphate pathway activity promotes pancreatic ductal adenocarcinoma progression via activating YAP/MMP1 axis under chronic acidosis

Background: Acidic microenvironment is a common physiological phenomenon in tumors, and is closely related to cancer development, but the effects of acidosis on pancreatic adenocarcinoma (PDAC) remains to be elucidated. Methods: Metabonomic assay and transcriptomic microarray were used to detect the...

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Detalles Bibliográficos
Autores principales: Chen, Siyuan, Ning, Bo, Song, Jinwen, Yang, Zihan, Zhou, Li, Chen, Zhiji, Mao, Linhong, Liu, Hongtao, Wang, Qingliang, He, Song, Zhou, Zhihang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990471/
https://www.ncbi.nlm.nih.gov/pubmed/35414794
http://dx.doi.org/10.7150/ijbs.69526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990471/
https://www.ncbi.nlm.nih.gov/pubmed/35414794
http://dx.doi.org/10.7150/ijbs.69526

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