Disruption of peroxisome proliferator-activated receptor α in hepatocytes protects against acetaminophen-induced liver injury by activating the IL-6/STAT3 pathway

Background & Aims: Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor abundantly expressed in liver. PPARα activator has been previously reported to protect against acetaminophen-induced hepatotoxicity, but fenofibrate, a lipid-lowering drug that acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhenzhen, Yao, Tiantian, Zhao, Nan, Liu, Hui, Cheng, Hao, Gonzalez, Frank J, Wang, Hua, Wang, Guiqiang, Qu, Aijuan, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990472/
https://www.ncbi.nlm.nih.gov/pubmed/35414769
http://dx.doi.org/10.7150/ijbs.69609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990472/
https://www.ncbi.nlm.nih.gov/pubmed/35414769
http://dx.doi.org/10.7150/ijbs.69609

Ejemplares similares