Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction

Due to increased drug and radiation tolerance, there is an urgent need to develop novel anticancer agents. In our previous study, we performed a series of structural modifications of ursolic acid (UA), a natural product of pentacyclic triterpenes, and found UA232, a derivative with stronger anti-tum...

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Detalles Bibliográficos
Autores principales: Gou, Wenfeng, Luo, Na, Yu, Bing, Wu, Hongying, Wu, Shaohua, Tian, Chen, Guo, Jianghong, Ning, Hongxin, Bi, Changfen, Wei, Huiqiang, Hou, Wenbin, Li, Yiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990475/
https://www.ncbi.nlm.nih.gov/pubmed/35414766
http://dx.doi.org/10.7150/ijbs.67166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990475/
https://www.ncbi.nlm.nih.gov/pubmed/35414766
http://dx.doi.org/10.7150/ijbs.67166

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