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IKZF1 selectively enhances homologous recombination repair by interacting with CtIP and USP7 in multiple myeloma

Rationale: In multiple myeloma (MM), the activities of non-homologous end joining (NHEJ) and homologous recombination repair (HR) are increased compared with healthy controls. Whether and how IKZF1 as an enhancer of MM participates in the DNA repair pathway of tumor cells remains elusive. Methods: W...

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Detalles Bibliográficos
Autores principales: Liu, Meng, Zhang, Ying, Wu, Yunzhao, Jin, Jin, Cao, Yang, Fang, Zhixiao, Geng, Lou, Yang, Li, Yu, Miao, Bu, Zhilei, Ji, Yanjie, Shan, Huizhuang, Zou, Zhihui, Liu, Ligen, Wang, Yingying, Zhang, Youping, Tong, Yin, Xu, Hanzhang, Lei, Hu, Liu, Wei, Gao, Fenghou, Wu, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990476/
https://www.ncbi.nlm.nih.gov/pubmed/35414773
http://dx.doi.org/10.7150/ijbs.70960