ALKBH5 Promotes Multiple Myeloma Tumorigenicity through inducing m(6)A-demethylation of SAV1 mRNA and Myeloma Stem Cell Phenotype

N6-methyladenosine (m(6)A) is the most prevalent modification to RNA in higher eukaryotes. ALKBH5 is an RNA demethylase that impacts RNA export and metabolism, and its aberrant expression is associated with the generation of tumours. In this study, we found that ALKBH5 was highly expressed in both p...

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Detalles Bibliográficos
Autores principales: Yu, Tingting, Yao, Lan, Yin, Hua, Teng, Yao, Hong, Mei, Wu, Qiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990482/
https://www.ncbi.nlm.nih.gov/pubmed/35414790
http://dx.doi.org/10.7150/ijbs.64943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990482/
https://www.ncbi.nlm.nih.gov/pubmed/35414790
http://dx.doi.org/10.7150/ijbs.64943

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