Computational approaches for the design of novel dopamine D(2) and serotonin 5-HT(2A) receptor dual antagonist towards schizophrenia

Piperidine and piperazine derivatives exhibit a diverse range of biological applications, including antipsychotic activity. In this study, a dataset of molecules containing piperidine, piperazine moieties that possess serotonin 5-HT(2A) and dopamine D(2) inhibitory activity have been chosen for Phar...

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Detalles Bibliográficos
Autores principales: Rathore, Akash, Asati, Vivek, Mishra, Mitali, Das, Ratnesh, Kashaw, Varsha, Kashaw, Sushil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990614/
https://www.ncbi.nlm.nih.gov/pubmed/35433192
http://dx.doi.org/10.1007/s40203-022-00121-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990614/
https://www.ncbi.nlm.nih.gov/pubmed/35433192
http://dx.doi.org/10.1007/s40203-022-00121-5

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