New insights into the genetic contribution of ALDH2 rs671 in pancreatic carcinogenesis: Evaluation by mediation analysis

A functional variant on ALDH2 rs671 (G>A) confers a protective effect against alcohol‐induced carcinogenesis through an indirect pathway mediated by decreased alcohol consumption. Conversely, this variant also contributes to the accumulation of carcinogenic agents, resulting in a direct carcinoge...

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Detalles Bibliográficos
Autores principales: Koyanagi, Yuriko N., Oze, Isao, Kasugai, Yumiko, Kawakatsu, Yukino, Taniyama, Yukari, Hara, Kazuo, Shimizu, Yasuhiro, Imoto, Issei, Ito, Hidemi, Matsuo, Keitaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990728/
https://www.ncbi.nlm.nih.gov/pubmed/35102643
http://dx.doi.org/10.1111/cas.15286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990728/
https://www.ncbi.nlm.nih.gov/pubmed/35102643
http://dx.doi.org/10.1111/cas.15286

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