MEK/ERK‐mediated oncogenic signals promote secretion of extracellular vesicles by controlling lysosome function

Cancer cells secrete large amounts of extracellular vesicles (EVs) originating from multivesicular bodies (MVBs). Mature MVBs fuse either with the plasma membrane for release as EVs, often referred as to exosomes or with lysosomes for degradation. However, the mechanisms regulating MVB fate remain u...

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Detalles Bibliográficos
Autores principales: Hikita, Tomoya, Uehara, Ryo, Itoh, Reina E., Mitani, Fumie, Miyata, Mamiko, Yoshida, Takuya, Yamaguchi, Rui, Oneyama, Chitose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990735/
https://www.ncbi.nlm.nih.gov/pubmed/35108425
http://dx.doi.org/10.1111/cas.15288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990735/
https://www.ncbi.nlm.nih.gov/pubmed/35108425
http://dx.doi.org/10.1111/cas.15288

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