Cargando…

CHIP‐associated mutant ASXL1 in blood cells promotes solid tumor progression

Clonal hematopoiesis of indeterminate potential (CHIP) is an age‐associated phenomenon characterized by clonal expansion of blood cells harboring somatic mutations in hematopoietic genes, including DNMT3A, TET2, and ASXL1. Clinical evidence suggests that CHIP is highly prevalent and associated with...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiaoxiao, Sato, Naru, Shimosato, Yuko, Wang, Teh‐Wei, Denda, Tamami, Chang, Yu‐Hsuan, Yabushita, Tomohiro, Fujino, Takeshi, Asada, Shuhei, Tanaka, Yosuke, Fukuyama, Tomofusa, Enomoto, Yutaka, Ota, Yasunori, Sakamoto, Takeharu, Kitamura, Toshio, Goyama, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990791/
https://www.ncbi.nlm.nih.gov/pubmed/35133065
http://dx.doi.org/10.1111/cas.15294