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Computational Prediction of Phosphoinositide Binding to Hyperpolarization-Activated Cyclic-Nucleotide Gated Channels

Protein-lipid interactions are key regulators of ion channel function. Numerous ion channels, including hyperpolarization-activated cyclic-nucleotide gated (HCN) channels have been shown to be regulated by phosphoinositides (PIPs), with important implications in cardiac and neuronal function. Specif...

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Detalles Bibliográficos
Autores principales: Claveras Cabezudo, Ainara, Feriel Khoualdi, Asma, D’Avanzo, Nazzareno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990809/
https://www.ncbi.nlm.nih.gov/pubmed/35399260
http://dx.doi.org/10.3389/fphys.2022.859087