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Imaging Unique DNA Sequences in Individual Cells Using a CRISPR-Cas9-Based, Split Luciferase Biosensor
An extensive arsenal of biosensing tools has been developed based on the clustered regularly interspaced short palindromic repeat (CRISPR) platform, including those that detect specific DNA sequences both in vitro and in live cells. To date, DNA imaging approaches have traditionally used full fluore...
Autores principales: | Heath, Nicholas G., O’Geen, Henriette, Halmai, Nicole B., Corn, Jacob E., Segal, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990833/ https://www.ncbi.nlm.nih.gov/pubmed/35403097 http://dx.doi.org/10.3389/fgeed.2022.867390 |
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