Micro-RNA let-7a-5p Derived From Mesenchymal Stem Cell-Derived Extracellular Vesicles Promotes the Regrowth of Neurons in Spinal-Cord-Injured Rats by Targeting the HMGA2/SMAD2 Axis

Spinal cord injury (SCI) often causes neuronal and axonal damage, resulting in permanent neurological impairments. Mesenchymal stem cells (MSCs) and extracellular vesicles (EVs) are promising treatments for SCI. However, the underlying mechanisms remain unclear. Herein, we demonstrated that EVs from...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Han, Tianyu, Guo, Ruocheng, Song, Peiwen, Liu, Yunlei, Wu, Zuomeng, Ai, Jichao, Shen, Cailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990843/
https://www.ncbi.nlm.nih.gov/pubmed/35401112
http://dx.doi.org/10.3389/fnmol.2022.850364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990843/
https://www.ncbi.nlm.nih.gov/pubmed/35401112
http://dx.doi.org/10.3389/fnmol.2022.850364

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