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Latent TGFβ-binding proteins 1 and 3 protect the larval zebrafish outflow tract from aneurysmal dilatation

Aortic root aneurysm is a common cause of morbidity and mortality in Loeys-Dietz and Marfan syndromes, where perturbations in transforming growth factor beta (TGFβ) signaling play a causal or contributory role, respectively. Despite the advantages of cross-species disease modeling, animal models of...

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Detalles Bibliográficos
Autores principales: Abrial, Maryline, Basu, Sandeep, Huang, Mengmeng, Butty, Vincent, Schwertner, Asya, Jeffrey, Spencer, Jordan, Daniel, Burns, Caroline E., Burns, C. Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990920/
https://www.ncbi.nlm.nih.gov/pubmed/35098309
http://dx.doi.org/10.1242/dmm.046979