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The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

In mice, rats, dogs and humans, the growth and function of sebaceous glands and eyelid Meibomian glands depend on the ectodysplasin signalling pathway. Mutation of genes encoding the ligand EDA, its transmembrane receptor EDAR and the intracellular signal transducer EDARADD leads to hypohidrotic ect...

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Detalles Bibliográficos
Autores principales: del-Pozo, Jorge, Headon, Denis J., Glover, James D., Azar, Ali, Schuepbach-Mallepell, Sonia, Bhutta, Mahmood F., Riddell, Jon, Maxwell, Scott, Milne, Elspeth, Schneider, Pascal, Cheeseman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990926/
https://www.ncbi.nlm.nih.gov/pubmed/35107126
http://dx.doi.org/10.1242/dmm.049034