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Programmable Cell-Free Transcriptional Switches for Antibody Detection

[Image: see text] We report here the development of a cell-free in vitro transcription system for the detection of specific target antibodies. The approach is based on the use of programmable antigen-conjugated DNA-based conformational switches that, upon binding to a target antibody, can trigger th...

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Detalles Bibliográficos
Autores principales: Patino Diaz, Aitor, Bracaglia, Sara, Ranallo, Simona, Patino, Tania, Porchetta, Alessandro, Ricci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990998/
https://www.ncbi.nlm.nih.gov/pubmed/35316049
http://dx.doi.org/10.1021/jacs.1c11706