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Ruthenium Polypyridyl Complex Bound to a Unimolecular Chair-Form G-Quadruplex

[Image: see text] The DNA G-quadruplex is known for forming a range of topologies and for the observed lability of the assembly, consistent with its transient formation in live cells. The stabilization of a particular topology by a small molecule is of great importance for therapeutic applications....

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Detalles Bibliográficos
Autores principales: McQuaid, Kane T., Takahashi, Shuntaro, Baumgaertner, Lena, Cardin, David J., Paterson, Neil G., Hall, James P., Sugimoto, Naoki, Cardin, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991003/
https://www.ncbi.nlm.nih.gov/pubmed/35324198
http://dx.doi.org/10.1021/jacs.2c00178