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Tryptophan Supplementation Increases the Production of Microbial-Derived AhR Agonists in an In Vitro Simulator of Intestinal Microbial Ecosystem

[Image: see text] The aryl hydrocarbon receptor (AhR) plays an important role in intestinal homeostasis, and some microbial metabolites of tryptophan are known AhR agonists. In this study, we assessed the impact of tryptophan supplementation on the formation of tryptophan metabolites, AhR activation...

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Detalles Bibliográficos
Autores principales: Koper, Jonna EB, Troise, Antonio Dario, Loonen, Linda MP, Vitaglione, Paola, Capuano, Edoardo, Fogliano, Vincenzo, Wells, Jerry M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991005/
https://www.ncbi.nlm.nih.gov/pubmed/35344652
http://dx.doi.org/10.1021/acs.jafc.1c04145