Hypoiodite-Catalyzed Oxidative Umpolung of Indoles for Enantioselective Dearomatization

[Image: see text] Here we report the oxidative umpolung of 2,3-disubstituted indoles toward enantioselective dearomative aza-spirocyclization to give the corresponding spiroindolenines using chiral quaternary ammonium hypoiodite catalysis. Mechanistic studies revealed the umpolung reactivity of C3 o...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiroki, Ukegawa, Naoya, Uyanik, Muhammet, Ishihara, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991020/
https://www.ncbi.nlm.nih.gov/pubmed/35319875
http://dx.doi.org/10.1021/jacs.2c01852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991020/
https://www.ncbi.nlm.nih.gov/pubmed/35319875
http://dx.doi.org/10.1021/jacs.2c01852

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