O-GlcNAcylation of MORC2 at threonine 556 by OGT couples TGF-β signaling to breast cancer progression

MORC family CW-type zinc finger 2 (MORC2) is a newly identified chromatin-remodeling enzyme involved in DNA damage response and gene transcription, and its dysregulation has been linked with Charcot-Marie-Tooth disease, neurodevelopmental disorder, and cancer. Despite its functional importance, how...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ying-Ying, Liu, Hong-Yi, Yu, Tian-Jian, Lu, Qin, Zhang, Fang-Lin, Liu, Guang-Yu, Shao, Zhi-Ming, Li, Da-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991186/
https://www.ncbi.nlm.nih.gov/pubmed/34974534
http://dx.doi.org/10.1038/s41418-021-00901-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991186/
https://www.ncbi.nlm.nih.gov/pubmed/34974534
http://dx.doi.org/10.1038/s41418-021-00901-0

Ejemplares similares