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Promiscuity mapping of the S100 protein family using a high-throughput holdup assay
S100 proteins are small, typically homodimeric, vertebrate-specific EF-hand proteins that establish Ca(2+)-dependent protein–protein interactions in the intra- and extracellular environment and are overexpressed in various pathologies. There are about 20 distinct human S100 proteins with numerous po...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991199/ https://www.ncbi.nlm.nih.gov/pubmed/35393447 http://dx.doi.org/10.1038/s41598-022-09574-2 |