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Syngeneically transplanted insulin producing cells differentiated from adipose derived stem cells undergo delayed damage by autoimmune responses in NOD mice

Insulin-producing cells (IPCs) generated by our established protocol have reached the non-clinical ‘proof of concept’ stage. Our strategy for their clinical application is the autotransplantation of IPCs into patients with type 1 diabetes mellitus (T1DM). In this context, the autoimmunity that chara...

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Detalles Bibliográficos
Autores principales: Tokuda, Kazunori, Ikemoto, Tetsuya, Yamashita, Shoko, Miyazaki, Katsuki, Okikawa, Shohei, Yamada, Shinichiro, Saito, Yu, Morine, Yuji, Shimada, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991208/
https://www.ncbi.nlm.nih.gov/pubmed/35393479
http://dx.doi.org/10.1038/s41598-022-09838-x