Identification of genetic effects underlying type 2 diabetes in South Asian and European populations

South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide association meta-analysis with South Asian T2D cases (n = 16,677) and controls (n = 33,856), followed by combined analyses with Europeans (n(eff) = 231,420). We identify 21 novel genetic loci for signific...

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Detalles Bibliográficos
Autores principales: Loh, Marie, Zhang, Weihua, Ng, Hong Kiat, Schmid, Katharina, Lamri, Amel, Tong, Lin, Ahmad, Meraj, Lee, Jung-Jin, Ng, Maggie C. Y., Petty, Lauren E., Spracklen, Cassandra N., Takeuchi, Fumihiko, Islam, Md. Tariqul, Jasmine, Farzana, Kasturiratne, Anuradhani, Kibriya, Muhammad, Mohlke, Karen L., Paré, Guillaume, Prasad, Gauri, Shahriar, Mohammad, Chee, Miao Ling, de Silva, H. Janaka, Engert, James C., Gerstein, Hertzel C., Mani, K. Radha, Sabanayagam, Charumathi, Vujkovic, Marijana, Wickremasinghe, Ananda R., Wong, Tien Yin, Yajnik, Chittaranjan S., Yusuf, Salim, Ahsan, Habibul, Bharadwaj, Dwaipayan, Anand, Sonia S., Below, Jennifer E., Boehnke, Michael, Bowden, Donald W., Chandak, Giriraj R., Cheng, Ching-Yu, Kato, Norihiro, Mahajan, Anubha, Sim, Xueling, McCarthy, Mark I., Morris, Andrew P., Kooner, Jaspal S., Saleheen, Danish, Chambers, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991226/
https://www.ncbi.nlm.nih.gov/pubmed/35393509
http://dx.doi.org/10.1038/s42003-022-03248-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991226/
https://www.ncbi.nlm.nih.gov/pubmed/35393509
http://dx.doi.org/10.1038/s42003-022-03248-5

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