TMEM189 negatively regulates the stability of ULK1 protein and cell autophagy

ULK1 is crucial for initiating autophagosome formation and its activity is tightly regulated by post-translational modifications and protein-protein interactions. In the present study, we demonstrate that TMEM189 (Transmembrane protein 189), also known as plasmanylethanolamine desaturase 1 (PEDS1),...

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Detalles Bibliográficos
Autores principales: Yu, Jiahong, Qu, Liujing, Xia, Yan, Zhang, Xuan, Feng, Jinqiu, Duan, Mengyuan, guo, Pengli, Lou, Yaxin, Lv, Ping, Lu, Wenping, Chen, Yingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991247/
https://www.ncbi.nlm.nih.gov/pubmed/35393404
http://dx.doi.org/10.1038/s41419-022-04722-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991247/
https://www.ncbi.nlm.nih.gov/pubmed/35393404
http://dx.doi.org/10.1038/s41419-022-04722-y

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