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TMEM189 negatively regulates the stability of ULK1 protein and cell autophagy
ULK1 is crucial for initiating autophagosome formation and its activity is tightly regulated by post-translational modifications and protein-protein interactions. In the present study, we demonstrate that TMEM189 (Transmembrane protein 189), also known as plasmanylethanolamine desaturase 1 (PEDS1),...
Autores principales: | Yu, Jiahong, Qu, Liujing, Xia, Yan, Zhang, Xuan, Feng, Jinqiu, Duan, Mengyuan, guo, Pengli, Lou, Yaxin, Lv, Ping, Lu, Wenping, Chen, Yingyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991247/ https://www.ncbi.nlm.nih.gov/pubmed/35393404 http://dx.doi.org/10.1038/s41419-022-04722-y |
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