Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics

Despite 50+ years of drug discovery, current antipsychotics have limited efficacy against negative and cognitive symptoms of schizophrenia, and are ineffective—with the exception of clozapine—against any symptom domain for patients who are treatment resistant. Novel therapeutics with diverse non-dop...

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Detalles Bibliográficos
Autores principales: Spark, Daisy L., Fornito, Alex, Langmead, Christopher J., Stewart, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991275/
https://www.ncbi.nlm.nih.gov/pubmed/35393394
http://dx.doi.org/10.1038/s41398-022-01904-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991275/
https://www.ncbi.nlm.nih.gov/pubmed/35393394
http://dx.doi.org/10.1038/s41398-022-01904-2

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