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Directed differentiation of human pluripotent stem cells to epicardial-derived fibroblasts

Cardiac fibroblasts (CFBs) are a key therapeutic target due to their supportive roles during heart development and response to injury and disease. Here, we describe a robust protocol to differentiate human pluripotent stem cells (hPSCs) into CFBs through an epicardial intermediate. We discuss in det...

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Detalles Bibliográficos
Autores principales: Floy, Martha E., Shabnam, Fathima, Palecek, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991283/
https://www.ncbi.nlm.nih.gov/pubmed/35403005
http://dx.doi.org/10.1016/j.xpro.2022.101275