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Connective tissue growth factor mediates bone morphogenetic protein 2-induced increase in hyaluronan production in luteinized human granulosa cells

BACKGROUND: Hyaluronan is the main component of the cumulus-oocyte complex (COC) matrix, and it maintains the basic structure of the COC during ovulation. As a member of the transforming growth factor β (TGF-β) superfamily, bone morphogenetic protein 2 (BMP2) has been identified as a critical regula...

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Detalles Bibliográficos
Autores principales: Chang, Hsun-Ming, Bai, Long, Zhu, Yi-Min, Leung, Peter C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991488/
https://www.ncbi.nlm.nih.gov/pubmed/35395768
http://dx.doi.org/10.1186/s12958-022-00937-y