Evaluating the clinical impact of routine whole genome sequencing in tuberculosis treatment decisions and the issue of isoniazid mono-resistance

BACKGROUND: The UK has implemented routine use of whole genome sequencing (WGS) in TB diagnostics. The WHO recommends addition of a fluoroquinolone for isoniazid mono-resistance, so early detection may be of use. The aim of this study was to describe the clinical utility and impact of WGS on treatme...

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Detalles Bibliográficos
Autores principales: Park, Mirae, Lalvani, Ajit, Satta, Giovanni, Kon, Onn Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991524/
https://www.ncbi.nlm.nih.gov/pubmed/35392842
http://dx.doi.org/10.1186/s12879-022-07329-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991524/
https://www.ncbi.nlm.nih.gov/pubmed/35392842
http://dx.doi.org/10.1186/s12879-022-07329-y

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