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Steroid-mediated liver steatosis is CD1d-dependent, while steroid-induced liver necrosis, inflammation, and metabolic changes are CD1d-independent

INTRODUCTION: Glucocorticoids contribute to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Natural killer T cells play a role in the pathogenesis of NAFLD and response to steroids. The present study aimed to determine the role of CD1d in steroid-mediated metabolic derangement and the...

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Detalles Bibliográficos
Autores principales: Adar, Tomer, Ya’acov, Ami Ben, Shabat, Yehudit, Mizrahi, Meir, Zolotarov, Lida, Lichtenstein, Yoav, Ilan, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991564/
https://www.ncbi.nlm.nih.gov/pubmed/35392825
http://dx.doi.org/10.1186/s12876-022-02242-9