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A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types

BACKGROUND: NOS2 expression is mostly found in bacteria-exposed or cytokine-treated tissues and is mostly connected to innate immune reactions. There are three isoforms of NOS2 (NOS2-1 to -3). In RNA-seq data sets, analyzing inflammatory gene expression, only expression of the NOS2-1 mRNA isoform is...

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Detalles Bibliográficos
Autores principales: Gather, Fabian, Ihrig-Biedert, Irmgard, Kohlhas, Paul, Krutenko, Tamara, Peitz, Michael, Brüstle, Oliver, Pautz, Andrea, Kleinert, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991583/
https://www.ncbi.nlm.nih.gov/pubmed/35392923
http://dx.doi.org/10.1186/s12964-022-00855-x